GO Terms |
Score |
Description |
GO:0003674 |
92.60% |
molecular_function |
GO:0098772 |
87.81% |
molecular function regulator |
GO:0030234 |
87.65% |
enzyme regulator activity |
GO:0004857 |
84.81% |
enzyme inhibitor activity |
GO:0030414 |
82.86% |
peptidase inhibitor activity |
GO:0061134 |
82.11% |
peptidase regulator activity |
GO:0004866 |
81.40% |
endopeptidase inhibitor activity |
GO:0061135 |
81.24% |
endopeptidase regulator activity |
GO:0004869 |
76.56% |
cysteine-type endopeptidase inhibitor activity |
GO:0005488 |
44.83% |
binding |
GO:0005515 |
42.86% |
protein binding |
GO:0002020 |
39.69% |
protease binding |
GO:0042802 |
37.73% |
identical protein binding |
GO:0019899 |
36.68% |
enzyme binding |
GO:0042277 |
29.80% |
peptide binding |
GO:0033218 |
29.31% |
amide binding |
GO:0001540 |
29.22% |
amyloid-beta binding |
GO:0004867 |
11.70% |
serine-type endopeptidase inhibitor activity |
GO:0005102 |
11.49% |
signaling receptor binding |
GO:0046983 |
11.36% |
protein dimerization activity |
GO:0042803 |
11.00% |
protein homodimerization activity |
GO:0008047 |
8.93% |
enzyme activator activity |
GO:0008289 |
8.52% |
lipid binding |
GO:0048018 |
7.51% |
receptor ligand activity |
GO:0043167 |
7.44% |
ion binding |
GO:0043168 |
7.34% |
anion binding |
GO:0001664 |
7.25% |
G protein-coupled receptor binding |
GO:0097159 |
7.16% |
organic cyclic compound binding |
GO:0030546 |
7.12% |
signaling receptor activator activity |
GO:0046914 |
6.82% |
transition metal ion binding |
GO:0005496 |
6.71% |
steroid binding |
GO:0043169 |
6.67% |
cation binding |
GO:0097367 |
6.60% |
carbohydrate derivative binding |
GO:0005543 |
6.44% |
phospholipid binding |
GO:0030545 |
6.41% |
receptor regulator activity |
GO:0044877 |
6.26% |
protein-containing complex binding |
GO:0005126 |
6.10% |
cytokine receptor binding |
GO:0005125 |
6.03% |
cytokine activity |
GO:0016787 |
6.03% |
hydrolase activity |
GO:0005539 |
5.66% |
glycosaminoglycan binding |
GO:0036094 |
5.54% |
small molecule binding |
GO:0003824 |
5.48% |
catalytic activity |
GO:0046872 |
5.45% |
metal ion binding |
GO:0005179 |
5.41% |
hormone activity |
GO:0043028 |
5.19% |
cysteine-type endopeptidase regulator activity involved in apoptotic process |
GO:1901681 |
5.01% |
sulfur compound binding |
GO:1901363 |
4.96% |
heterocyclic compound binding |
GO:0008201 |
4.56% |
heparin binding |
GO:0003676 |
4.55% |
nucleic acid binding |
GO:0070325 |
4.52% |
lipoprotein particle receptor binding |
GO:0043027 |
4.49% |
cysteine-type endopeptidase inhibitor activity involved in apoptotic process |
GO:0016788 |
4.46% |
hydrolase activity, acting on ester bonds |
GO:0060089 |
4.45% |
molecular transducer activity |
GO:0042379 |
4.34% |
chemokine receptor binding |
GO:0038023 |
4.19% |
signaling receptor activity |
GO:0008270 |
4.10% |
zinc ion binding |
GO:0019207 |
3.92% |
kinase regulator activity |
GO:0005507 |
3.89% |
copper ion binding |
GO:0042562 |
3.86% |
hormone binding |
GO:0019887 |
3.75% |
protein kinase regulator activity |
GO:0019900 |
3.65% |
kinase binding |
GO:0042056 |
3.62% |
chemoattractant activity |
GO:0005509 |
3.60% |
calcium ion binding |
GO:0003823 |
3.48% |
antigen binding |
GO:0043178 |
3.45% |
alcohol binding |
GO:0005319 |
3.45% |
lipid transporter activity |
GO:0019901 |
3.41% |
protein kinase binding |
GO:0008009 |
3.40% |
chemokine activity |
GO:0032934 |
3.39% |
sterol binding |
GO:0035091 |
3.31% |
phosphatidylinositol binding |
GO:0031210 |
3.30% |
phosphatidylcholine binding |
GO:0034987 |
3.28% |
immunoglobulin receptor binding |
GO:0099106 |
3.25% |
ion channel regulator activity |
GO:0004888 |
3.22% |
transmembrane signaling receptor activity |
GO:0003779 |
3.21% |
actin binding |
GO:0070405 |
3.18% |
ammonium ion binding |
GO:0008092 |
3.10% |
cytoskeletal protein binding |
GO:0050997 |
3.04% |
quaternary ammonium group binding |
GO:0120013 |
3.01% |
lipid transfer activity |
GO:0046982 |
3.01% |
protein heterodimerization activity |
GO:0005215 |
2.99% |
transporter activity |
GO:0003723 |
2.96% |
RNA binding |
GO:0008144 |
2.88% |
drug binding |
GO:0003677 |
2.87% |
DNA binding |
GO:0051082 |
2.81% |
unfolded protein binding |
GO:0015485 |
2.80% |
cholesterol binding |
GO:0032813 |
2.75% |
tumor necrosis factor receptor superfamily binding |
GO:0031072 |
2.74% |
heat shock protein binding |
GO:0019840 |
2.66% |
isoprenoid binding |
GO:0051087 |
2.66% |
chaperone binding |
GO:0019210 |
2.65% |
kinase inhibitor activity |
GO:0031406 |
2.59% |
carboxylic acid binding |
GO:0008083 |
2.55% |
growth factor activity |
GO:0048020 |
2.52% |
CCR chemokine receptor binding |
GO:0019904 |
2.50% |
protein domain specific binding |
GO:0043177 |
2.45% |
organic acid binding |
GO:0030246 |
2.41% |
carbohydrate binding |
GO:0140096 |
2.41% |
catalytic activity, acting on a protein |
GO:0019209 |
2.40% |
kinase activator activity |
GO:0005549 |
2.40% |
odorant binding |
GO:0005501 |
2.39% |
retinoid binding |
GO:0030295 |
2.39% |
protein kinase activator activity |
GO:0033293 |
2.38% |
monocarboxylic acid binding |
GO:0005246 |
2.37% |
calcium channel regulator activity |
GO:0004860 |
2.35% |
protein kinase inhibitor activity |
GO:0016247 |
2.26% |
channel regulator activity |
GO:0033612 |
2.20% |
receptor serine/threonine kinase binding |
GO:0071814 |
2.20% |
protein-lipid complex binding |
GO:0071813 |
2.18% |
lipoprotein particle binding |
GO:0019838 |
2.17% |
growth factor binding |
GO:0120015 |
2.14% |
sterol transfer activity |
GO:0030971 |
2.12% |
receptor tyrosine kinase binding |
GO:0016209 |
2.10% |
antioxidant activity |
GO:0016298 |
2.10% |
lipase activity |
GO:0060589 |
2.09% |
nucleoside-triphosphatase regulator activity |
GO:1990782 |
2.08% |
protein tyrosine kinase binding |
GO:0008200 |
2.07% |
ion channel inhibitor activity |
GO:0050839 |
2.07% |
cell adhesion molecule binding |
GO:0052689 |
2.05% |
carboxylic ester hydrolase activity |
GO:0005184 |
2.05% |
neuropeptide hormone activity |
GO:0051117 |
2.04% |
ATPase binding |
GO:0016740 |
1.98% |
transferase activity |
GO:0005158 |
1.97% |
insulin receptor binding |
GO:0004620 |
1.97% |
phospholipase activity |
GO:0016853 |
1.94% |
isomerase activity |
GO:0016248 |
1.94% |
channel inhibitor activity |
GO:0016597 |
1.93% |
amino acid binding |
GO:0004518 |
1.86% |
nuclease activity |
GO:0020037 |
1.86% |
heme binding |
GO:0046906 |
1.85% |
tetrapyrrole binding |
GO:0005506 |
1.84% |
iron ion binding |
GO:0005198 |
1.83% |
structural molecule activity |
GO:0047485 |
1.81% |
protein N-terminus binding |
GO:0016829 |
1.80% |
lyase activity |
GO:0005546 |
1.80% |
phosphatidylinositol-4,5-bisphosphate binding |
GO:0016798 |
1.80% |
hydrolase activity, acting on glycosyl bonds |
GO:0071855 |
1.73% |
neuropeptide receptor binding |
GO:0001530 |
1.73% |
lipopolysaccharide binding |
GO:0004519 |
1.72% |
endonuclease activity |
GO:0005201 |
1.70% |
extracellular matrix structural constituent |
GO:0019955 |
1.70% |
cytokine binding |
GO:1901981 |
1.67% |
phosphatidylinositol phosphate binding |
GO:0015248 |
1.67% |
sterol transporter activity |
GO:0004623 |
1.66% |
phospholipase A2 activity |
GO:0015026 |
1.66% |
coreceptor activity |
GO:0035254 |
1.66% |
glutamate receptor binding |
GO:0044389 |
1.62% |
ubiquitin-like protein ligase binding |
GO:0072341 |
1.61% |
modified amino acid binding |
GO:0048306 |
1.61% |
calcium-dependent protein binding |
GO:0015631 |
1.60% |
tubulin binding |
GO:0005518 |
1.59% |
collagen binding |
GO:0008233 |
1.56% |
peptidase activity |
GO:0016859 |
1.55% |
cis-trans isomerase activity |
GO:0000166 |
1.55% |
nucleotide binding |
GO:0030544 |
1.53% |
Hsp70 protein binding |
GO:0005216 |
1.53% |
ion channel activity |
GO:1901265 |
1.52% |
nucleoside phosphate binding |
GO:0005096 |
1.52% |
GTPase activator activity |
GO:0005504 |
1.51% |
fatty acid binding |
GO:0008017 |
1.51% |
microtubule binding |
GO:0004540 |
1.51% |
ribonuclease activity |
GO:0016810 |
1.51% |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
GO:0097110 |
1.51% |
scaffold protein binding |
GO:0016504 |
1.49% |
peptidase activator activity |
GO:0005178 |
1.48% |
integrin binding |
GO:0043021 |
1.48% |
ribonucleoprotein complex binding |
GO:0050750 |
1.48% |
low-density lipoprotein particle receptor binding |
GO:0031369 |
1.44% |
translation initiation factor binding |
GO:0030674 |
1.42% |
protein binding, bridging |
GO:0031420 |
1.40% |
alkali metal ion binding |
GO:0031625 |
1.38% |
ubiquitin protein ligase binding |
GO:0016301 |
1.37% |
kinase activity |
GO:0080025 |
1.37% |
phosphatidylinositol-3,5-bisphosphate binding |
GO:0060090 |
1.37% |
molecular adaptor activity |
GO:0043539 |
1.36% |
protein serine/threonine kinase activator activity |
GO:0140299 |
1.36% |
small molecule sensor activity |
GO:0042165 |
1.36% |
neurotransmitter binding |
GO:0019208 |
1.36% |
phosphatase regulator activity |
GO:0008081 |
1.35% |
phosphoric diester hydrolase activity |
GO:0022857 |
1.35% |
transmembrane transporter activity |
GO:0004553 |
1.35% |
hydrolase activity, hydrolyzing O-glycosyl compounds |
GO:0001786 |
1.34% |
phosphatidylserine binding |
GO:0019842 |
1.33% |
vitamin binding |
GO:0051020 |
1.32% |
GTPase binding |
GO:0030695 |
1.32% |
GTPase regulator activity |
GO:0004930 |
1.31% |
G protein-coupled receptor activity |
GO:0016491 |
1.31% |
oxidoreductase activity |
GO:0140098 |
1.30% |
catalytic activity, acting on RNA |
GO:0005048 |
1.30% |
signal sequence binding |
GO:0003785 |
1.29% |
actin monomer binding |
GO:0051427 |
1.29% |
hormone receptor binding |
GO:0016772 |
1.28% |
transferase activity, transferring phosphorus-containing groups |
GO:0004622 |
1.28% |
lysophospholipase activity |
GO:1902936 |
1.27% |
phosphatidylinositol bisphosphate binding |
GO:0051879 |
1.27% |
Hsp90 protein binding |
GO:0030247 |
1.27% |
polysaccharide binding |
GO:0019199 |
1.27% |
transmembrane receptor protein kinase activity |
GO:0005261 |
1.26% |
cation channel activity |
GO:0031267 |
1.26% |
small GTPase binding |
GO:0051015 |
1.26% |
actin filament binding |
GO:0140272 |
1.26% |
exogenous protein binding |
GO:0043621 |
1.26% |
protein self-association |
GO:0003755 |
1.25% |
peptidyl-prolyl cis-trans isomerase activity |
GO:0015075 |
1.25% |
ion transmembrane transporter activity |
GO:0051861 |
1.24% |
glycolipid binding |
GO:0004672 |
1.24% |
protein kinase activity |
GO:0042578 |
1.24% |
phosphoric ester hydrolase activity |
GO:0030599 |
1.24% |
pectinesterase activity |
GO:0070851 |
1.23% |
growth factor receptor binding |
GO:0015267 |
1.23% |
channel activity |
GO:0060590 |
1.23% |
ATPase regulator activity |
GO:0005547 |
1.21% |
phosphatidylinositol-3,4,5-trisphosphate binding |
GO:0008022 |
1.21% |
protein C-terminus binding |
GO:0001618 |
1.21% |
virus receptor activity |
GO:0051428 |
1.21% |
peptide hormone receptor binding |
GO:0050840 |
1.20% |
extracellular matrix binding |
GO:0001968 |
1.20% |
fibronectin binding |
GO:0022803 |
1.19% |
passive transmembrane transporter activity |
GO:0003678 |
1.19% |
DNA helicase activity |
GO:0005262 |
1.18% |
calcium channel activity |
GO:0070273 |
1.17% |
phosphatidylinositol-4-phosphate binding |
GO:0019902 |
1.17% |
phosphatase binding |
GO:0048037 |
1.16% |
cofactor binding |
GO:0032553 |
1.15% |
ribonucleotide binding |
GO:0015459 |
1.15% |
potassium channel regulator activity |
GO:0004675 |
1.14% |
transmembrane receptor protein serine/threonine kinase activity |
GO:0022890 |
1.14% |
inorganic cation transmembrane transporter activity |
GO:0043394 |
1.14% |
proteoglycan binding |
GO:0022836 |
1.13% |
gated channel activity |
GO:0003735 |
1.13% |
structural constituent of ribosome |
GO:0023023 |
1.13% |
MHC protein complex binding |
GO:0045296 |
1.12% |
cadherin binding |
GO:0004674 |
1.12% |
protein serine/threonine kinase activity |
GO:0042287 |
1.12% |
MHC protein binding |
GO:0019212 |
1.11% |
phosphatase inhibitor activity |
GO:1901567 |
1.10% |
fatty acid derivative binding |
GO:0044183 |
1.10% |
protein folding chaperone |
GO:0017076 |
1.10% |
purine nucleotide binding |
GO:0005516 |
1.10% |
calmodulin binding |
GO:0046625 |
1.09% |
sphingolipid binding |
GO:0016773 |
1.09% |
phosphotransferase activity, alcohol group as acceptor |
GO:0070492 |
1.07% |
oligosaccharide binding |
GO:0051787 |
1.07% |
misfolded protein binding |
GO:0019888 |
1.07% |
protein phosphatase regulator activity |
GO:0048029 |
1.07% |
monosaccharide binding |
GO:0003729 |
1.07% |
mRNA binding |
GO:0023026 |
1.07% |
MHC class II protein complex binding |
GO:0051019 |
1.06% |
mitogen-activated protein kinase binding |
GO:0008324 |
1.06% |
cation transmembrane transporter activity |
GO:0016812 |
1.06% |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides |
GO:0005164 |
1.05% |
tumor necrosis factor receptor binding |
GO:0015318 |
1.05% |
inorganic molecular entity transmembrane transporter activity |
GO:0070011 |
1.04% |
peptidase activity, acting on L-amino acid peptides |
GO:0019239 |
1.04% |
deaminase activity |
GO:0005548 |
1.03% |
phospholipid transporter activity |
GO:0016894 |
1.03% |
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters |
GO:0030551 |
1.02% |
cyclic nucleotide binding |
GO:0140110 |
1.01% |
transcription regulator activity |
GO:0043325 |
1.01% |
phosphatidylinositol-3,4-bisphosphate binding |
GO:0019001 |
1.01% |
guanyl nucleotide binding |